Neuronal oscillations and epilepsy research group

The COVID-19 pandemic has meant change and disruption for many, including those in the creative community. All over the world and in Ireland artists, innovators, designers and have seen their opportunities slow down with gigs, plays, exhibitions and other events moved online or cancelled worldwide. Science Gallery wanted to support and collaborate with our community, and with that in mind, we launched a new round of experimental grants: virtual residencies available for makers, creators, writers, artists and designers in Ireland. Over the past two months, 18 artists in residence have been paired with advisors drawn from groups of experts at Science Gallery at Trinity College Dublin and other supporting cultural partners. Find about more about the researchers involved and the artists themselves as they share their process, experiences and thoughts so far. This project has been funded in part by the Provost's Academic Development Fund from Trinity College Dublin.

Full title: Experimental models of physiological cortical rhythms in live human brain tissue: translational biomarkers for CNS drug development, Mark Cunningham (Newcastle University, UK)

READ THE PAPER: http://bit.ly/2G3nZfi Many patients with mitochondrial disease have neurological symptoms, including drug-refractory epilepsy. Chan et al. develop an in vitro model of mitochondrial epilepsy with face and predictive validity. The model provides mechanistic insights into the role of astrocytes and the GABA-glutamate-glutamine cycle in driving seizure generation.

Mark is the Ellen Mayston Bates Professor of Neurophysiology of Epilepsy at Trinity College Dublin. He was appointed to this position in 2018. He completed his PhD in Neurophysiology at the University of Bristol in 2001 and has held positions at Bristol, Leeds, Heidelberg and Newcastle. His research aims to understand how pathological electrical activity is generated by the epileptic brain. He previously sat on the Scientific Advisory Committee for Epilepsy Research UK, is a member of the Brain Tumour-Related Epilepsy international research consortium and has recently joined the TASK1 working group of the ILAE/AES Joint Translational Task Force